I-SP-H001-Eshushu iThengisa iNkozo yeMdiliya enyulu ngeProanthocyanidin (GSE) 95% yeAnti-Aging and Anti-Wrinkle

Igama lesiLatini: Intsholongwane yevinifera L

Usapho:Vitaceae

I-Genus:Umkhuhlane

Inxalenye esetyenzisiweyo:Imbewu

Iinkcukacha:

Proanthocyanidins 95%

Polyphenol 80%

WUkunyibilika emanzini 95%

Imbali

Imbewu yomdiliya (isikhumba) sisicatshulwa esiphuma kwimbewu (yesikhumba) sediliya.Imbewu (isikhumba) eshiyekileyo kwimveliso yewayini okanye ijusi iyavunwa, icolwe kwaye ikhutshwe.Banomxholo ophezulu weekhompawundi ezaziwa ngokuba zii-OPCs (oligomeric proanthocyanidins). Ukususela ekubeni umphandi ongumFrentshi, uGqr Jack Masquelier wahlukanisa ii-OPCs kwisikhumba se-peanut ngo-1947, i-OPC.s ifunyenwe kwizityalo ezininzi kwaye iye yabhengezwa njenge-antioxidant enamandla ye-non-toxic, non-mutagenic, non-carcinogenic, kwaye ayinayo imiphumo emibi ngokuqwalasela uphando oluninzi.

Umsebenzi

Umthamo we-antioxidant weMbewu yoMdiliya (ulusu) Uphuma kwiproanthocyanidins (oligomeric proanthocyanidins) (OPCs).Ngamandla e-antioxidant ngamaxesha angama-20 anamandla kune-Vitamin C kunye namaxesha angama-50 anamandla kune-Vitamin E , ii-OPCs iyaziwa njenge-antioxidant enamandla yokwenza i-neutralize radicals yamahhala, edlala indima enkulu kwizifo eziphazamisayo, izifo zentliziyo, ukungaboni kakuhle, umonakalo welanga kunye nokuguga kwangaphambili.

1.Izifo zentliziyo

Uphando luye lwaqinisekisa ukuba ii-OPCs inceda ukuqinisa ii-capillaries, i-arteries kunye ne-veins, nto leyo eyenza ukuba ibe nezicelo ezibalulekileyo zeklinikhi.Ii-OPC zibonakala zizinzisa iindonga zemithambo yegazi, zinciphisa ukuvuvukala, kwaye zixhasa ngokubanzi izicubu eziqukethe i-collagen kunye ne-elastin. 

1). I-Atherossteosis:

Kuye kwangqinwa ukuba i-oxidation ye-LDL idlala indima ebalulekileyo kwi-atherosclerosis.Ngomsebenzi wayo ogqwesileyo wokulwa ne-antioxidant, ii-OPCs ziphelisa umonakalo owenziwe yi-radicals yasimahla, kunye ne-collagenase kunye ne-elastinase kwimithambo, ngaloo ndlela ikhusela okanye ibuyisela umva i-atherosclerosis.Ubungqina bezilwanyana bucebisa ukuba ii-OPC zinokucotha okanye zibuyisele umva i-atherosclerosis. 

2).Ukunqongophala kweVen (Imithambo yeVaricose)

I-Varicose Veins ibhekisela kwimeko xa amachibi egazi emilenzeni, ebangela intlungu, ubunzima, ukuvuvukala, ukukhathala, kunye nemithanjeni engabonakaliyo.Ngokuqinisa i-capillary kunye nokunciphisa i-capillary osmosis, ii-OPCs zinokukhulula iintlungu kunye nokudumba kokusilela kwe-venous.Ngesizathu sinye, ii-OPC ziyacetyiswa njengonyango lwe-hemorrhoids ngokunjalo.Kukho nobungqina bokuba ii-OPCs zinokuba luncedo ekudumbeni okuhlala kulandela ukwenzakala okanye utyando.  Ii-OPC zibonakala zikhawuleza ukunyamalala kokudumba, ngokomeleza igazi elonakeleyo kunye nemithambo ye-lymph evuzayo ulwelo.

Uphononongo oluphindwe kabini oluyimfama olulawulwa yi-placebo lwezifundo ze-92 lufumene ukuba ii-OPC, ezithathwe kwi-dose ye-100 mg ngamaxesha e-3 imihla ngemihla, ziphucule kakhulu iimpawu eziphambili, kubandakanywa ubunzima, ukuvuvukala, kunye nokuphazamiseka komlenze. Kwisithuba senyanga ye-1, i-75% yabathathi-nxaxheba baphathwa ngee-OPCs baphuculwe kakhulu.Olunye uphononongo olulawulwa yi-placebo olubhalise abantu abangama-364 abanemithambo ye-varicose lufumanise ukuba unyango ngee-OPCs luvelise iziphumo ezingaphezulu kwezo ze-placebo. 

3). I-retinopathy / Ukuphuculwa koMbono

Amandla e-OPCs ekomelezeni i-capillary kunye nokunciphisa i-capillary osmosis iyasebenza kwizigulana ezinesifo sohlangothi kunye ne-retinopathy.I-OPCs ibonakaliswe ukuba iphucula i-retinopathy ebangelwa sisifo seswekile, i-atherosclerosis, ukuvuvukala kunye nokuguga.Kwakhona kuye kwaxelwa ukuba ii-OPC zinokukhawulezisa ukubuyiswa kombono emva kokukhanya okuqinileyo, kwaye ziphucule i-acuity yombono wabo bakhathazwa kukudinwa kwamehlo ngenxa yokusebenzisa ikhompyuter ixesha elide.

Uphononongo lweveki ezi-6, olulawulwayo (kodwa alumfamekanga) luvavanye isakhono sembewu yomdiliya (isikhumba) ii-OPCs zokuphucula ukubona ebusuku kwizifundo eziqhelekileyo. Kulo vavanyo lwamavolontiya anempilo e-100, abo bafumana i-200 mg ngosuku lwe-OPCs babonisa ukuphuculwa kombono wobusuku kunye nokubuyisela ukukhanya kwe-glare xa kuthelekiswa nezifundo ezingaphendulwanga.

2. Ukuguga / isifo se-Alzheimer

Ngenxa yokuba ii-OPCs zinokudlula ngokulula i-Blood-Brain Barrier, inokuthintela ngokufanelekileyo umonakalo owenziwa yi-radicals yamahhala kwi-brain organism, ukuze isifo se-Alzheimer sithintelwe kwaye sitshintshwe.

3. Ukukhathalelwa kolusu

Ngenxa yomsebenzi wayo wokulwa ne-antioxidant, ii-OPC zicingelwa ukuba zikhusela ulusu kwimitha ye-ultraviolet ephezulu kunye neeradicals zamahhala.Ubungqina obuninzi bubonisa ukuba ii-OPCs zikhusela kwaye zomeleza i-collagen kunye ne-elastin yolusu, ukuze imibimbi ithintelwe kwaye ukuqina kolusu kugcinwe. I-OPCs kwifomu yekhrimu yonyango oludumileyo lwesikhumba esiguga, kwithiyori yokuba ngokulungisa i-elastin kunye ne-collagen baya kubuyisela ulusu kwimbonakalo yolutsha.

4.Anti-umhlaza, Anti-ukudumba kunye Anti- allergic Umsebenzi

Kuba iiradicals zasimahla zidlala indima ebalulekileyo ekwenziweni kwethumba, ii-OPCs zisetyenziselwa umsebenzi wazo wokuchasana nomhlaza.Kwakhona ngenxa yokuthintela kwayo izinto ezivuthayo ezifana ne-PG, i-5-HT kunye ne-Leukotriene, kunye nokubopha okukhethiweyo kwi-tissue edibeneyo yamalungu ukukhulula intlungu kunye nokudumba, ii-OPCs ziluncedo kwiintlobo ze-arthritis.Umsebenzi ochasayo we-OPCs ucingelwa ukuba sisiphumo se-anti-histamine.Xa kuthelekiswa namanye amayeza achasene nokwalana, ii-OPCs zisebenza ngendlela efanayo kwaye azinaziphumo ebezingalindelekanga ezifanayo njengokukozela.

IKhemistri

Le Mveliso yenziwe ngeprocyanidolic oligomers (OPCs).Iifomula zesakhiwo ziyalandelwa:

Inkcazo